Abdul Wajid Bhat Ph.D

Scientist D/Ramanujan Fellow

Department of Clinical Biochemistry

Unversity of Kashmir














 We use budding yeast to study how chromatin organization is established, propagated, maintained, and changed during various cellular processes. 




Research Grants

  1. Chromatin Dynamics associated with transcription Elongation. (DST-SERB,  New Delhi)

  2. Understanding the role of Protein Kinase CK2 in prevention of spurious intragenic transcription. (DST-SERB,  New Delhi)




Lab members

  1. Saima Nazir (Ph. D student)

  2. Ambreena Farooq (Ph. D student)





  1. Casein kinase 2 mediated phosphorylation of Spt6 modulates histone dynamics and regulates spurious transcription. Gouot E, Bhat W, Rufiange A, Fournier E, Paquet E, Nourani A. Nucleic Acids Res. 2018 Jun

  2. Purification of Yeast Native Reagents for the Analysis of Chromatin Function-I: Nucleosomes for Reconstitution and Manipulation of Histone Marks. Lacoste N, Bhat W, Côté J. Methods Mol Biol. 2017;1528:39-51.

  3. Purification of Yeast Native Reagents for the Analysis of Chromatin Function-II: Multiprotein Complexes and Biochemical Assays. Lacoste N, Bhat W, Côté J. Methods Mol Biol. 2017;1528:53-67.

  4. TINTIN, at the interface of chromatin, transcription elongation, and mRNA processing. Bhat W, Ahmad S, Côté J. RNA Biol. 2015;12(5):486-9.

  5. Casein kinase 2 associates with the yeast chromatin reassembly factor Spt2/Sin1 to regulate its function in the repression of spurious transcription. Bhat W, Boutin G, Rufiange A, Nourani A. Mol Cell Biol. 2013 Nov;33(21):4198-211.

  6. Transcription regulation by the noncoding RNA SRG1 requires Spt2-dependent chromatin deposition in the wake of RNA polymerase II. Thebault P, Boutin G, Bhat W, Rufiange A, Martens J, Nourani A. Mol Cell Biol. 2011 Mar;31(6):1288-300.

  7. Genome-wide replication-independent histone H3 exchange occurs predominantly at promoters and implicates H3 K56 acetylation and Asf1. Rufiange A, Jacques PE, Bhat W, Robert F, Nourani A. Mol Cell. 2007 Aug 3;27(3):393-405.

  8. Antimicrobial activity of marine bacteria associated with sponges from the waters off the coast of South East India. Anand TP, Bhat AW, Shouche YS, Roy U, Siddharth J, Sarma SP. Microbiol Res. 2006;161(3):252-62.